Download PDF by Vural Gökmen: Acrylamide in food : analysis, content and potential health

By Vural Gökmen

ISBN-10: 0128028327

ISBN-13: 9780128028322

ISBN-10: 0128028750

ISBN-13: 9780128028759

Acrylamide in foodstuff: research, content material and strength future health results provides the new analytical methodologies for acrylamide detection, up to date information regarding its prevalence in quite a few meals (such as bakery items, fried potato items, espresso, battered items, water, desk olives etc.), and its interplay mechanisms and future health results.

The publication is designed for nutrition scientists, technologists, toxicologists, and foodstuff staff, offering a useful business reference publication that also is perfect for educational libraries that hide the domain names of nutrition creation or nutrients technological know-how.

As the realm future health association has declared that acrylamide represents a possible health and wellbeing threat, there was, lately, a rise in fabric at the formation and presence of acrylamide in several meals. This publication compiles and synthesizes that info in one resource, therefore allowing these in a single self-discipline to get to grips with the thoughts and purposes in different disciplines of meals technological know-how.

  • Provides most up-to-date details on acrylamide in numerous meals (bakery items, fried potato items, espresso, battered items, water, desk olives, etc.)
  • Explores acrylamide within the nutrients chain within the context of injury, akin to acrylamide and melanoma, neuropathology of acrylamide, maternal acrylamide and results on offspring and its poisonous results in tissues
  • Touches on quite a few matters, together with acrylamide, excessive heated meals, nutritional acrylamide, acrylamide formation, N-acetyl-S-(2-carbamoylethyl)-cysteine (AAMA), acrylamide elimination, L-asparaginase, and acrylamide determination
  • Presents contemporary analytical methodologies for acrylamide choice, together with liquid chromatographic tandem mass spectrometry and gasoline chromatography-mass spectrometry

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Additional resources for Acrylamide in food : analysis, content and potential health effects

Sample text

Acrylamide occurrence databases often assemble data from different countries, because of a lack of country-specific analytic data on acrylamide content in foods, thus reducing the specificity of country-specific acrylamide estimates. Availability of only one replicate of 24-HR; the sporadic nature of consumption of some acrylamide-rich food items (crisps, fried potatoes, and so on) results in large day-to-day variability in 24-HR estimates. It is well accepted that dietary self-report instruments suffer from bias due to measurement errors, and thus do not provide accurate measures of intake in general.

MINI DICTIONARY Hazard A chemical agent in food with the potential to cause harm (relates to the inherent properties of the substance that make it capable of causing adverse effects). Risk The probability of occurrence of an adverse health effect, weighted for its severity, that may result from the exposure under defined conditions to a chemical hazard in food. Margin of Exposure (MoE) The carcinogenic effects of acrylamide follow a genotoxic mechanism, hence no health-based guidance values (such as the ADI/TDI) are available.

The International Agency for Research on Cancer has classified acrylamide as a group 2A (probably carcinogenic to humans) based on sufficient animal evidence and limited human evidence. 5 μg/kg BW per day: 1000–10,000 times lower than doses in rodent studies. Acrylamide is metabolized in the body to glycidamide by cytochrome P450 enzymes (CYP2E1). It is readily absorbed and distributed to all tissues. Both acrylamide and glycidamide are excreted in urine as mercapturic acids. Glycidamide is much more reactive than acrylamide with DNA and metabolism of acrylamide to glycidamide appears to be a prerequisite for the genotoxicity of acrylamide in vitro and in experimental animals.

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Acrylamide in food : analysis, content and potential health effects by Vural Gökmen


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